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Pfizer, Loughberg, Ireland |
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Process gas venting |
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Background |
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This Pfizer
facility in Loughberg manufactures proprietary active
ingredients for strong prescription drugs which are then shipped
to other facilities, predominantly Lipitor, for finishing.
Remaining capacity is allocated to cancer drug manufacture.
Most processes in the facility utilize a glass lined reactor
vessel to produce large volumes of solvents such as ethyl
chloride, acetone, etc. Chlorine gas and hydrochloric acid
condensate are process by-products that require attention.
The vapors of all reacted processes are collected and either
reclaimed by distillation or routed to a vent header to be
incinerated. |
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Attached to each
reactor are fluoropolymer lined piping systems up to 12"
diameter with pressure ratings ranging from 40 bar or 150 psi
and full vacuum. A fast acting check valve separates this
reactor system from the vent header and protects the header from
damage due to excessive pressure. System pressure
specification downstream from this check valve drops to plus and
minus 300 millibar (120" wc or 4.35 psi). The largest
portion of the vent system is a 36" diameter, 300 foot long
header routed along the periphery of the facility. This
header terminates at a flame arrestor connected to the inlet of
a large thermal oxidizer. |
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Challenge |
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Pfizer appreciated
the permanence of fluoropolymer products but lined pipe products
over 12 inches in diameter were cost prohibitive. They
therefore opted to install fabricated heavy stainless steel pipe
for the vent header. A pipe thickness specification was
established based on a set chemical erosion rate for stainless
steel and with the aim of replacing the pipe at scheduled
intervals. The increased pipe thickness resulted in
significantly heavier parts which in turn made handling and
installation more difficult. Heavier parts also required
heavier and more costly support structures. |
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Solution |
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PSP® products with
fluoropolymer coating were perceived as a desirable alternative solution
to the periodic pipe replacement scenario. The lighter
construction of PSP® made the cost of both materials and
installation attractive as opposed to very long lead times and
higher costs for alternative custom lined components. A
heavier wall PSP® was designed in 8 foot lengths for this
application and installed in 1998 at a contract value of just
over $500k USD. |
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Conclusions |
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This application
demonstrates the versatility of PSP® as a product highly suited
to the highly corrosive gas abatement demands of the
pharmaceutical industry. Combining engineering
capabilities with vertically integrated manufacturing, Fab-Tech
provided the best solution for Pfizer. This included
coordination of international sea freight in order to
accommodate a tight installation schedule. |
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